| Autor: |
Evelina Polmickaitė-Smirnova, Irina Buchovec, Saulius Bagdonas, Edita Sužiedėlienė, Arūnas Ramanavičius, Žilvinas Anusevičius |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Journal of photochemistry and photobiology. B, Biology. 231 |
| ISSN: |
1873-2682 |
| Popis: |
The photodynamic inactivation (PDI) represents the potential alternative to traditional antibiotic therapy, and can be applied to treat various bacterial infections, including those caused by Gram-negative bacterial strains. One of the treatment modalities is based on the capacity of bacterial cells to synthesize the excess amounts of porphyrins after exposure to an externally applied 5-aminolevulinic acid (5-ALA), which makes them photosensitive and leads to reduced survival after irradiation with an appropriately selected light source. This study focuses on the sensitization and the photoinduced inactivation of Salmonella enterica cells in PBS containing 0.5 mM 5-ALA, incubated at 37 °C for 4 h or for 20 h and afterwards irradiated with violet LED light (11.1 mW/cm |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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