Effect of boric acid on oxidative stress in rats with fetal alcohol syndrome
| Autor: | Mine Inal, Melis Savasan Sogut, Kazim Kartkaya, Güngör Kanbak, Kevser Kusat Ol, Ibrahim Sogut, Aysegul Oglakci |
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| Přispěvatelé: | Sogut, I., Oglakci, A., Kartkaya, K., Ol, K.K., Sogut, M.S., Kanbak, G., Inal, M.E., Yeditepe Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
malondialdehyde
Cancer Research medicine.medical_specialty Antioxidant medicine.medical_treatment Fetal alcohol syndrome Alcohol Superoxide dismutase medicine.disease_cause chemistry.chemical_compound Immunology and Microbiology (miscellaneous) Internal medicine Malondialdehyde Medicine glutathione peroxidase chemistry.chemical_classification biology business.industry Glutathione peroxidase catalase General Medicine Articles medicine.disease Boric acid Catalase superoxide dismutase Endocrinology chemistry Immunology biology.protein business fetal alcohol syndrome Oxidative stress boric acid |
| Zdroj: | Experimental and Therapeutic Medicine |
| Popis: | To the best of our knowledge, this is the first study concerning the effect of boric acid (BA) administration on fetal alcohol syndrome (FAS). In this study, the aim was to investigate prenatal alcohol-induced oxidative stress on the cerebral cortex of newborn rat pups and assess the protective and beneficial effects of BA supplementation on rats with FAS. Pregnant rats were divided into three groups, namely the control, alcohol and alcohol + boric acid groups. As markers of alcohol-induced oxidative stress in the cerebral cortex of the newborn pups, malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) levels were measured. Although the MDA levels in the alcohol group were significantly increased compared with those in the control group (P |
| Databáze: | OpenAIRE |
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