Drugs used in viral diseases – their mechanism of action, selected adverse effects and safety during pregnancy and lactation
| Autor: | Kamil Dyrka, Katarzyna Łącka, Edyta Szałek, Miłosz Miedziaszczyk |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Pregnancy viral diseases business.industry lcsh:R lcsh:Medicine Physiology medicine.disease antiviral drugs 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Infectious Diseases medicine.anatomical_structure Mechanism of action Lactation adverse effects Medicine 030212 general & internal medicine antivirals during pregnancy and lactation medicine.symptom business Adverse effect |
| Zdroj: | Postępy Higieny i Medycyny Doświadczalnej, Vol 73, Pp 491-507 (2019) |
| ISSN: | 1732-2693 0032-5449 |
| DOI: | 10.5604/01.3001.0013.5249 |
| Popis: | Viruses cause many diseases in humans, from self-resolving diseases to acute fatal diseases. New antiviral drugs are registered and the efficacy and safety of other medicines are evaluated in clinical trials. Antiviral therapy significantly reduces the morbidity and mortality of patients, but may cause numerous adverse effects. The aim of this study is to discuss the mechanism, selected adverse effects of available antivirals and their safety during pregnancy and lactation. The authors refer to the classification of drugs used during pregnancy and recommendations for breastfeeding, which, for example, definitely prohibit the use of ribavirin. The authors also pay attention to the monitoring of selected diagnostic parameters to improve the treatment results. Clinicians should limit adverse effects through an individual, specific to the patient treatment regimen. Physicians should pay special attention to the use of antiviral drugs in pregnant and breast-feeding women. Clinical trials should be continued to increase knowledge about the adverse effects of antiviral medicines. |
| Databáze: | OpenAIRE |
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