Pre- and postmenopausal breast cancer
| Autor: | Rush Bf, Dimarco Pe, Miller Fw, Grobstein N, Levitt Jw, Najem Gr, Roellke Se |
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| Rok vydání: | 1982 |
| Předmět: |
Risk
medicine.medical_specialty Epidemiology Population Breast Neoplasms Breast cancer screening Breast cancer medicine Humans education Gynecology education.field_of_study medicine.diagnostic_test Obstetrics business.industry Public Health Environmental and Occupational Health Place of birth Middle Aged medicine.disease Menstruation Parity Breast Feeding Relative risk Menarche Marital status Female Menopause business Epidemiologic Methods Breast feeding Contraceptives Oral |
| Zdroj: | Preventive medicine. 11(3) |
| ISSN: | 0091-7435 |
| Popis: | It has been postulated that breast cancer is not a single disease, and that the risk factors occurring in premenopausal women are different from those occurring in postmenopausal women. This case-control study of pre- and postmenopausal breast cancer was designed to investigate a variety of variables including age of menarche, parity, age at first full-term birth, breast feeding patterns, age at menopause, and history of oral contraceptive use. The study compared 60 breast cancer cases and 125 matched controls from the same breast cancer screening population. Cases and controls were matched for race, age, place of birth, marital status, education, and annual family income. More cases than controls used oral contraceptives; the differences were statistically significant. The risk ratio estimates were 2.9 (confidence intervals 1.19-7.15). The mean duration of oral contraceptive use was more than two times longer among premenopausal breast cancer cases than controls and five times longer among postmenopausal cases than the controls. The breast cancer cases had significantly more relatives with a history of other cancers than the control group (risk ratio estimate 2.3, P |
| Databáze: | OpenAIRE |
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