A new tumor biomarker, serum protein peak at 3,144 m/z, in patients with node-positive breast cancer
| Autor: | Zhongping Chen, D. Su, S. Xu, Xiongjun Wang, Wei Liu, H. Yang, S. Xie, X. Meng, L. Lei |
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| Jazyk: | angličtina |
| Předmět: |
CA15-3
Adult Serum medicine.medical_specialty Pathology Cancer Research medicine.medical_treatment Breast Neoplasms Gastroenterology Breast cancer Internal medicine medicine Biomarkers Tumor Humans Family history Stage (cooking) Aged Proportional Hazards Models Chemotherapy Proportional hazards model business.industry Mucin-1 CD24 Antigen General Medicine Middle Aged medicine.disease 3 144 m/z protein peak Oncology Lymphatic Metastasis Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization SELDI–TOF MS Biomarker (medicine) Female business Body mass index Research Article |
| Zdroj: | Clinical & Translational Oncology |
| ISSN: | 1699-048X |
| DOI: | 10.1007/s12094-014-1264-9 |
| Popis: | Purpose To explore the association between the 3,144 m/z protein peak and the clinicopathological features and prognosis in breast cancer. Methods Using SELDI–TOF MS, we analyzed serum protein peak at 3,144 m/z in 283 patients with node-positive breast cancer, its relationship with clinicopathological features and their prognosis evaluating value of survival. Results 3,144 m/z positive rate was higher in elderly patients (42.8 % in ≥50-year-old vs. 31.2 % in |
| Databáze: | OpenAIRE |
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