Multidrug-resistant pneumococci (serotype 8) causing invasive disease in HIV+ patients
| Autor: | E. Cercenado, Mercedes Marín, B. Ramos, Iciar Rodríguez-Avial, Emilio Bouza, J. C. Sanz, Carmen Ardanuy |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Microbiology (medical) Serotype Adolescent Erythromycin HIV Infections Microbial Sensitivity Tests Drug resistance Biology medicine.disease_cause Pneumococcal Infections Microbiology Young Adult Drug Resistance Multiple Bacterial Streptococcus pneumoniae Prevalence medicine Humans multidrug-resistant pneumococci Typing Serotyping Child Aged Aged 80 and over Sweden Streptococcus pneumoniae serotypes Infant General Medicine vaccines Middle Aged Virology Anti-Bacterial Agents Electrophoresis Gel Pulsed-Field Multiple drug resistance Penicillin Infectious Diseases Child Preschool Multilocus sequence typing Female HIV-infected patients Multilocus Sequence Typing medicine.drug |
| Zdroj: | Clinical Microbiology and Infection. 17:1094-1098 |
| ISSN: | 1198-743X |
| DOI: | 10.1111/j.1469-0691.2011.03495.x |
| Popis: | From July 2007 to June 2009, all pneumococci causing invasive pneumococcal disease in our hospital were serotyped. Antimicrobial susceptibility was determined by microdilution. Molecular typing was performed by pulsed-field gel electrophoresis and by multilocus sequence typing. Among 251 invasive pneumococci, serotype 8 was the most frequent (13.5%). All serotype 8 strains were susceptible to penicillin; however, 61.8% (21/34) were co-resistant to erythromycin, levofloxacin and tetracycline and identical to the Sweden15A-ST63 clone. Serotype 8 was significantly more frequent among human immunodeficiency virus (HIV)-infected patients (36.5%). The high prevalence of this nonconjugate vaccine multiresistant serotype 8 is a cause for concern mainly in HIV-infected patients. |
| Databáze: | OpenAIRE |
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