Additive effect of Lygodium venustum SW. in association with gentamicin
| Autor: | Jacqueline Cosmo Andrade, Henrique Douglas Melo Coutinho, Saulo R. Tintino, Antônio A.F. Saraiva, Teógenes M. Souza, Maria Flaviana Bezerra Morais-Braga, Gláucia M.M. Guedes, Celestina E. Sobral-Souza, José Galberto Martins da Costa, Karla K.A. Santos |
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| Rok vydání: | 2015 |
| Předmět: |
Staphylococcus aureus
medicine.drug_class Antibiotics Drug Evaluation Preclinical Plant Science Microbial Sensitivity Tests Biology Biochemistry Analytical Chemistry Toxicology 03 medical and health sciences 0302 clinical medicine Drug Resistance Multiple Bacterial medicine Escherichia coli Lygodium venustum Traditional medicine Ethanol Plant Extracts Organic Chemistry Drug Synergism Anti-Bacterial Agents Resistant bacteria 030220 oncology & carcinogenesis Ferns Gentamicin Gentamicins 030217 neurology & neurosurgery medicine.drug |
| DOI: | 10.6084/m9.figshare.1568123 |
| Popis: | The aim of this work was to evaluate the interactions between gentamicin and the ethanol extract of the fern Lygodium venustum SW (EELV). The ethanol extract of L. venustum was obtained, the phytocompounds were identified and the EELV was assayed by the checkerboard method with gentamicin against two bacterial strains multiresistant to antibiotics. The antibiotic activity of gentamicin, when associated with the extract, was enhanced in an additive manner against both strains. The results indicated that L. venustum can be a source of secondary metabolites to be used in association with antibiotics as aminoglycosides in the antibiotic chemotherapy against resistant bacteria. |
| Databáze: | OpenAIRE |
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