Very low birth weight infants born to cytomegalovirus-seropositive mothers fed with their mother's milk: a prospective study
| Autor: | Maria Grazia Capretti, Sara Pignatelli, Giacomo Faldella, Liliana Gabrielli, Luigi Corvaglia, Marcello Lanari, Tiziana Lazzarotto, Elisabetta Tridapalli |
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| Přispěvatelé: | Capretti MG, Lanari M, Lazzarotto T, Gabrielli L, Pignatelli S, Corvaglia L, Tridapalli E, Faldella G. |
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Male
Human cytomegalovirus Pediatrics medicine.medical_specialty Neonatal intensive care unit Birth weight Congenital cytomegalovirus infection Cytomegalovirus Urine Breast milk Antibodies Viral Pregnancy medicine Humans Infant Very Low Birth Weight Pregnancy Complications Infectious preterm infants CMV human milk Milk Human business.industry Infant Newborn Infant food and beverages Gestational age virus diseases medicine.disease Infectious Disease Transmission Vertical Low birth weight Cytomegalovirus Infections DNA Viral Pediatrics Perinatology and Child Health Female medicine.symptom business Breast feeding |
| Popis: | OBJECTIVE: To assess the risk of post-natal cytomegalovirus (CMV) transmission to very low birth weight (VLBW) infants fed with their mother's fresh milk. STUDY DESIGN: Prospective, observational study of 80 VLBW infants and their 68 mothers. Infants' urine and their own mother's fresh breast milk were tested for CMV by means of culture tests once a week until discharge. CMV in infected milk and urine were genotyped. The clinical course, laboratory findings, and outcome of infants infected with CMV at 2 years of age are reported. RESULTS: Fifty-three mothers (78%) were CMV-seropositive at delivery. CMV was detected in the milk of 21 of 53 seropositive mothers (40%), and CMV was in the urine in 9 of 26 infants (35%) fed with CMV-positive milk. The same gN-genotype was found in milk and urine. Three infected infants |
| Databáze: | OpenAIRE |
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