Seroepidemiology of hepatitis A and E virus infections in Tehran, Iran: a population based study
| Autor: | Mohammad Amin Pourhoseingholi, Peter Karayiannis, Manijeh Habibi, Pedram Azimzadeh, Seyed Mohammad Ebrahim Tahaei, Hamed Naghoosi, Seyed Reza Mohebbi, Mohammad Reza Zali, Mohammad Rostami Nejad |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Cross-sectional study viruses Iran medicine.disease_cause Hepatitis E virus Seroepidemiologic Studies Surveys and Questionnaires Prevalence Medicine Child Aged 80 and over education.field_of_study virus diseases Hepatitis A General Medicine Middle Aged Hepatitis E Vaccination Infectious Diseases Child Preschool Population Surveillance Female Adult Adolescent Population Enzyme-Linked Immunosorbent Assay Virus Young Adult Age Distribution Humans Seroprevalence Hepatitis Antibodies Sex Distribution education Aged Immunization Programs business.industry Public Health Environmental and Occupational Health Infant medicine.disease Virology digestive system diseases Cross-Sectional Studies Immunoglobulin G Immunology Parasitology business |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene. 106:528-531 |
| ISSN: | 0035-9203 |
| DOI: | 10.1016/j.trstmh.2012.05.013 |
| Popis: | Hepatitis A virus (HAV) and hepatitis E virus (HEV) are enteric hepatotropic viruses and their prevalence is related to the sanitary conditions of the region under investigation. There are only a few studies on the seroepidemiology of these two viruses in the general Iranian population. The purpose of this investigation was to measure the prevalence of hepatitis A and E infections in the general population. Between 2006 and 2007, a cross sectional study was performed in Tehran, Iran. Blood specimens were collected and questionnaires were filled in for 551 persons. Patient sera were tested by ELISA for anti-HEV and anti-HAV IgGs. The χ(2) test and independent t-test were used for statistical analysis and p0.05 was considered significant. The overall seroprevalence rates of anti-HEV IgG and anti-HAV IgG were 9.3% and 90%, respectively. The prevalence of antibodies to HAV and HEV was greater among men than women and increased with age. However, there was no significant relationship between age and gender with the existence of anti- HAV and HEV IgG antibodies. Our results show the seroprevalence of HAV and HEV antibodies are high and both viruses are endemic in this region. These findings are in accordance with results obtained from previous studies. We recommend that foreign travelers to Iran are vaccinated against HAV. |
| Databáze: | OpenAIRE |
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