Antidepressant tapering strips to help people come off medication more safely
Autor: | Peter C. Groot, Jim van Os |
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Přispěvatelé: | RS: MHeNs - R2 - Mental Health, Psychiatrie & Neuropsychologie, MUMC+: MA Psychiatrie (3) |
Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Harm reduction
drug withdrawal symptoms tapering patient medication knowledge DISCONTINUATION Tapering Antidepressants EFFICACY 030227 psychiatry Discontinuation 03 medical and health sciences Psychiatry and Mental health Antidepressant medication antipsychotics 0302 clinical medicine Drug withdrawal symptoms Anesthesia SCHIZOPHRENIA Antidepressant 030212 general & internal medicine Patient Medication Knowledge harm reduction Psychology Short duration |
Zdroj: | Psychosis-Psychological Social and Integrative Approaches, 10(2), 142-145. Routledge/Taylor & Francis Group |
ISSN: | 1752-2447 1752-2439 |
Popis: | Antidepressants are commonly prescribed for many mental disorders, including psychosis. Withdrawal effects, resulting from inappropriately short duration of tapering or lack of flexibility in prescribing gradual reduction, are common. An observational study was conducted of the use of tapering strips, which allow gradual dosage reduction and minimise the potential for withdrawal effects. A tapering strip consists of antidepressant medication, packaged in a roll of small daily pouches, each with the same or slightly lower dose than the one before it. Strips come in series covering 28days. Of 1194 users of tapering strips, 895 (75%) wished to discontinue their antidepressant medication. In these 895, median length of antidepressant use was 2-5years (IQR: 1-2years->10years). Nearly two-thirds (62%) had unsuccessfully attempted withdrawal before (median = 2 times before, IQR 1-3). Almost all of these (97%) had experienced some degree of withdrawal, with 49% experiencing severe withdrawal (7 on a scale of 1-7, IQR 6-7). The most common medications were paroxetine (n=423, 47%) and venlafaxine (n=386, 43%). Of the 895 wishing to discontinue, 636 (71%) succeeded in tapering their antidepressant medication completely, using a median of 2 tapering strips (IQR 1-3) over a median of 56days (IQR=28-84). Tapering strips represent a simple and effective method of achieving a gradual dosage reduction. |
Databáze: | OpenAIRE |
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