Interbirth Interval Is Associated With Childhood Type 1 Diabetes Risk
| Autor: | Christine L. Roberts, Girts Brigis, G. Devoti, B. Urbonaite, Christopher Cardwell, Vaiva Sadauskaite-Kuehne, Constantin Ionescu-Tirgoviste, Thomas Waldhoer, Emma Jane Kirsty Wadsworth, Carine de Beaufort, Edith Schober, Gyula Soltész, Johnny Ludvigsson, Roger C Parslow, Christopher Patterson, Jannet Svensson |
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| Přispěvatelé: | Cardwell, Cr, Svensson, J, Waldhoer, T, Ludvigsson, J, Sadauskaité Kuehne, V, Roberts, Cl, Parslow, Rc, Wadsworth, Ej, Brigis, G, Urbonaité, B, Schober, E, Devoti, Gabriele, Ionescu Tirgoviste, C, de Beaufort, Ce, Patterson, C. C. |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Pediatrics medicine.medical_specialty Medicin och hälsovetenskap Time Factors medicine Multidisciplinaire généralités & autres [D99] [Sciences de la santé humaine] Endocrinology Diabetes and Metabolism Birth weight Pathophysiology Medical and Health Sciences Pregnancy Risk Factors Diabetes mellitus Internal Medicine Birth Weight Humans Sibling Child Multidisciplinary general & others [D99] [Human health sciences] Type 1 diabetes business.industry Confounding Odds ratio medicine.disease Birth order Diabetes Mellitus Type 1 Female Birth Order business |
| Zdroj: | Diabetes, 61(3), 702-707. Alexandria, VA: American Diabetes Association (2012). Diabetes |
| Popis: | Short interbirth interval has been associated with maternal complications and childhood autism and leukemia, possibly due to deficiencies in maternal micronutrients at conception or increased exposure to sibling infections. A possible association between interbirth interval and subsequent risk of childhood type 1 diabetes has not been investigated. A secondary analysis of 14 published observational studies of perinatal risk factors for type 1 diabetes was conducted. Risk estimates of diabetes by category of interbirth interval were calculated for each study. Random effects models were used to calculate pooled odds ratios (ORs) and investigate heterogeneity between studies. Overall, 2,787 children with type 1 diabetes were included. There was a reduction in the risk of childhood type 1 diabetes in children born to mothers after interbirth intervals |
| Databáze: | OpenAIRE |
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