Prevalence of Anti-Cytomegalovirus Anticorps in Children at the Chantal Biya Foundation Mother Child Centre, Cameroon

Autor: Essola Josiane Kikie, Nna Hermine, Ngondi Grace, Bamia Alice, Pondy Angèle, Djim-Adjim-Ngana Karyom, EmboloEnyegueElisée Libert, Adiogo Dieudonnée
Rok vydání: 2022
DOI: 10.5281/zenodo.7329114
Popis: The cytomegalovirus is an infectious pathogen that causes a disease that can cause major difficulties in infants, allograft recipients, and people with any type of immunodeficiency. Because of their exposure to contaminating elements, developing countries are the most afflicted, with a prevalence of 97 percent in Cameroonian adults. It's an illness with a high cumulative incidence for which paediatric epidemiological data is scarce. Furthermore, the efficacy of measures to prevent transmission is poorly understood. The goal of this study was to determine the prevalence of anti-cytomegalovirus antibodies among newborns in order to provide better prenatal care. Methods: From January to May 2015, a prospective cross-sectional study with a descriptive goal was undertaken at the Chantal Biya Foundation's Mother and Child Centre in Yaoundé. The data was collected using a technical form that included demographic information and an Immunoglobulin G ELISA type serological test to assess the children's serological status. Results: We chose 188 children aged 0 days to 12 years from our study population, with an average age of 3 ± 4 years. CMV was found to be present in 66% of the people in our research. Between the ages of 0 and 24, the prevalence was high and constant.After a drop in prevalence between 25 and 36 months, the prevalence of CMV steadily increased from 43.5 to 77.8% between 25 and 12 years of age. Apart from age, no other factor was discovered to predispose to HIV infection. Conclusion: The prevalence of cytomegalovirus in children aged 0-12 years in our population was high and increased with age.
Databáze: OpenAIRE