The correlation between ferritin level and acute phase parameters in rheumatoid arthritis and systemic lupus erythematosus
| Autor: | Gülsüm Emel Pamuk, Serkan Seyhan, Ömer Nuri Pamuk, Necati Çakir |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test biology Transferrin saturation business.industry Acute-phase protein Hematocrit medicine.disease Gastroenterology Ferritin Iron-deficiency anemia immune system diseases Erythrocyte sedimentation rate Internal medicine Rheumatoid arthritis Immunology medicine Serum iron biology.protein skin and connective tissue diseases business Original Investigation |
| Popis: | Objective: In this study, we evaluated the relationship between ferritin levels and disease activation in rheumatoid arthritis (RA) patients. Material and Methods: We included 44 patients with RA, 20 patients with systemic lupus erythematosus (SLE), 25 patients with infection, 22 patients with malignancy, and 20 healthy control subjects. Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), whole blood count, and serum iron parameters were determined in all cases. The joint findings in RA patients were recorded, and disease activity score (DAS) was calculated. In SLE patients, antinuclear antibody (ANA) and anti-dsDNA titers and C3 and C4 complement levels were determined. SLE disease activity index (SLEDAI) score was calculated. Results: Serum ferritin levels in the RA, SLE, and control groups were lower than those in the infection and malignancy groups (p |
| Databáze: | OpenAIRE |
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