Viability of Cartilage Grafts in Various Forms
| Autor: | Cemal, Firat, Ali, Gurlek, Nasuhi Engin, Aydin, Nasuhi Engin, Aydn |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Preparation stage Biocompatible Materials Cartilage graft Transplantation Autologous Statistics Nonparametric Cryopreservation medicine Animals Transplantation Homologous Perichondrium Cellulose Oxidized Fascia business.industry Cartilage Graft Survival Significant difference General Medicine Anatomy Surgery Resorption surgical procedures operative medicine.anatomical_structure Otorhinolaryngology Rabbits Ear Cartilage business |
| Zdroj: | Journal of Craniofacial Surgery. 22:1666-1670 |
| ISSN: | 1049-2275 |
| DOI: | 10.1097/scs.0b013e31822f3b1f |
| Popis: | The viability of cartilage grafts, in many forms, has been researched since the using of cartilage grafts in surgical proce- dures. Cryopreservation period and viability of cartilage grafts have remained unclear. This study was performed to investigate the du- rability, viability, and behavior of fresh or cryopreserved cartilage grafts when used as autografts or allografts in various forms. Six cartilage grafts (1 of each preparation type; 3 blocks and 3 diced) were prepared by wrapping with Surgicel or autogenous fascia, or they were left bare. After the graft preparation stage, the cartilage grafts were inserted into pockets prepared on the dorsum of each rabbit. Groups 1, 2, 3, and 4 (6 rabbits in each group) received autogenous fresh grafts, allogenous fresh grafts, autogenous cryo- preserved grafts, and allogenous cryopreserved grafts, respectively. All cartilage grafts were implanted for 2 months. At the end of the second month, specimens were harvested and analyzed. The bare grafts provided the most viable specimens. There was no significant difference between the frozen or fresh and allo- graft or autograft groups with respect to viability and resorption ratios. The bare block graft, in all groups, survived significantly more than the other graft types. Allografts (homografts), similar autografts, did not create major problems, and they had excellent host tolerance and low antigenic- ity, especially when the perichondrium was removed. Viability and durability of the bare grafts (diced and block) were better than fascia or Surgicel-wrapped cartilage graft forms. |
| Databáze: | OpenAIRE |
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