A One-Pot Approach to 2,3-Diarylbenzo[ b]furans through N-Heterocyclic Carbene-Catalyzed 1,6-Conjugate Addition Followed by Acid Mediated Dehydrative Annulation

Autor:	Prithwish Goswami, Gurdeep Singh, Ramasamy Vijaya Anand, Sonam Sharma
Rok vydání:	2018
Předmět:	chemistry.chemical_compound Annulation chemistry 010405 organic chemistry Furan Organic Chemistry 010402 general chemistry 01 natural sciences Medicinal chemistry Carbene 0104 chemical sciences Conjugate Catalysis
Zdroj:	The Journal of organic chemistry. 83(17)
ISSN:	1520-6904
Popis:	A one-pot protocol for the synthesis of 2,3-diarylbenzo[ b]furan derivatives through an N-heterocyclic carbene catalyzed 1,6-conjugate addition of aromatic aldehydes to 2-hydroxyphenyl-substituted para-quinone methides followed by acid-mediated dehydrative annulation has been developed. This protocol allowed us to access a wide range of 2,3-diarylbenzo[ b]furan derivatives in moderate to good yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da90997ab24bbb1af0120f4a02bc923 https://pubmed.ncbi.nlm.nih.gov/30028613 Zobrazit plný text záznamu