Outcomes of Cystectomy with MAINZ Pouch II and Epispadias Repair in Exstrophy Epispadias Complex in Adults: A Single-centre Experience from Pakistan
| Autor: | Usman Qamar, Tanzeel Guzdar, Syed Adibul Hasan Rizvi, Manzoor Hussain, Quratul Ain Ghori, Saeed Abidi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Epispadias Adolescent Urinary system medicine.medical_treatment Renal function Cystectomy Malignancy Young Adult Enuresis medicine Humans Pakistan business.industry Bladder Exstrophy Rectum General Medicine medicine.disease Surgery Transplantation Pouch medicine.symptom business |
| Zdroj: | Journal of the College of Physicians and Surgeons Pakistan. 31:1191-1195 |
| ISSN: | 1681-7168 1022-386X |
| DOI: | 10.29271/jcpsp.2021.10.1191 |
| Popis: | OBJECTIVE To evaluate surgical outcomes and renal functions after cystectomy + MAINZ Pouch II and epispadias repair as a staged procedure in adult patients with exstrophy epispadias complex (EEC). STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY Department of Urology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, from January 2004 to December 2020. METHODOLOGY A total of 33 patients with EEC were treated. Out of which, 20 underwent cystectomy + MAINZ Pouch II with epispadias repair as a staged procedure. Out of these, 17 had a follow-up period of more than a year and were included in the study. The patients were followed up after 6 weeks of surgery, at 6 months, one year, and at the end of follow-up. The assessed variables included the patients' renal function tests, malignancy potential, morning erections, ejaculations, night emissions, day-and-night-time urinary frequency, and overall happiness of patients at the end of follow-up. RESULTS The mean age was 25.1 ± 7.5 years and mean follow-up duration was 7.8 ± 5.2 years. Postoperatively, there was a rise in blood urea from 27.8 to 35.08 mg/dl with a concurrent fall in serum bicarbonate from a mean of 23.5 to 20.2 mEq/dl. All patients were continent during the day-time postoperatively; whereas, two patients experienced nocturnal enuresis. All male patients exhibited good erections and ejaculations, but there was persistence of dorsal chordae in 4 (23.3%) patients. All were delighted, happy and pleased with the surgical outcomes and had returned to normal life. No rectal or sigmoid malignancy was observed. CONCLUSION In adult EEC patients, cystectomy + MAINZ Pouch II and epispadias repair is safe and effective. Key Words: Adults, Exstrophy epispadias complex, MAINZ pouch II, Pakistan. |
| Databáze: | OpenAIRE |
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