Green-Emitting 4,5-Diaminonaphthalimides in Activity-Based Probes for the Detection of Thrombin

Autor:	Maciej Krzeszewski, Sylwia Modrzycka, Manon H. E. Bousquet, Denis Jacquemin, Marcin Drąg, Daniel T. Gryko
Rok vydání:	2022
Předmět:	Naphthalimides Organic Chemistry Thrombin Electrons Physical and Theoretical Chemistry Biochemistry Fluorescent Dyes
Zdroj:	Organic letters. 24(30)
ISSN:	1523-7052
Popis:	The natures of electron-donating groups as well as the bridge between them determine the fate of substituted 1,8-naphthalimide molecules in the excited state. An activity-based probe constructed from a selective peptide sequence, a reactive warhead, and the brightest green-emitting fluorophore displays impressive performance for thrombin protease detection in a newly constructed series of 1,8-naphthalimides.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da131e5588dfa6d11e8f942b6425b2c https://pubmed.ncbi.nlm.nih.gov/35863755 Zobrazit plný text záznamu