A case of superficial spreading melanoma in situ 2.5 mm in diameter
| Autor: | Kazufumi Yoneda, Toshiyuki Seko, Makoto Yanagihara, Masanori Ban, Shunji Mori |
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| Rok vydání: | 1993 |
| Předmět: |
In situ
Pathology medicine.medical_specialty Cytoplasm Skin Neoplasms Large tumor Dermatology Lesion Skin surface medicine Humans Pigmented lesion Melanoma Cell Size Cell Nucleus Melanins Leg Chemistry General Medicine Anatomy Middle Aged medicine.disease Superficial spreading melanoma HMB-45 medicine.anatomical_structure Female Epidermis medicine.symptom |
| Zdroj: | The Journal of dermatology. 20(7) |
| ISSN: | 0385-2407 |
| Popis: | A 60-year-old woman with superficial spreading melanoma in situ, measuring 2.5 mm in diameter, was examined. She had noticed a very small pigmented lesion 1.2 mm in diameter on her left lower leg in April of 1989. By April of 1990, it had grown to 2.5 mm in diameter. Its edge was irregular, and its color was variegated black to brown. Skin surface markings had disappeared in the center portion. Histopathologically, the lesion was asymmetrical. Atypical large cells nested in the lower epidermis and were scattered singly in the mid and upper epidermis, as seen in Paget's disease. At the periphery of the lesion, single large tumor cells were scattered in the mid epidermis. The tumor cells reacted to monoclonal anti-melanoma antibody HMB-45. |
| Databáze: | OpenAIRE |
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