Advantages and disadvantages of mouse models of chronic lymphocytic leukemia in drug discovery
| Autor: | Dolors Colomer, Fabian Arenas, Heribert Playa-Albinyana |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0303 health sciences
Drug discovery business.industry Chronic lymphocytic leukemia Mice Transgenic medicine.disease Leukemia Lymphocytic Chronic B-Cell Peripheral blood Disease Models Animal Mice 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Lymphoid malignancy immune system diseases hemic and lymphatic diseases 030220 oncology & carcinogenesis Drug Discovery medicine Cancer research Animals Bone marrow CD5 business 030304 developmental biology |
| Zdroj: | Expert Opinion on Drug Discovery. 16:1085-1090 |
| ISSN: | 1746-045X 1746-0441 |
| DOI: | 10.1080/17460441.2021.1935860 |
| Popis: | Chronic lymphocytic leukemia (CLL) is a lymphoid malignancy characterized by the proliferation and accumulation of mature CD5+ B cells in the peripheral blood (PB), bone marrow (BM) and lymphoid ti... |
| Databáze: | OpenAIRE |
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