The influence of mechanical forces on the glycosaminoglycan content of the rabbit flexor digitorum profundus tendon
| Autor: | Paul G. Bell-booth, Helen C. Reilly, M. H. Flint, Gerald C. Gillard |
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| Rok vydání: | 1979 |
| Předmět: |
viruses
medicine.medical_treatment Tendon Transfer Normal values Hindlimb Biochemistry Dermatan sulfate Glycosaminoglycan Tendons chemistry.chemical_compound Rheumatology Tendon transfer Hyaluronic acid medicine Animals Orthopedics and Sports Medicine Chondroitin sulfate Molecular Biology Glycosaminoglycans Chemistry Cell Biology Anatomy musculoskeletal system Tendon medicine.anatomical_structure Biophysics Rabbits Stress Mechanical |
| Zdroj: | Connective tissue research. 7(1) |
| ISSN: | 0300-8207 |
| Popis: | The physical forces acting on the flexor digitorum profundus tendon of the rabbit were altered by anterior translocation of the tendon. The glycosaminoglycan (GAG) content was determined in regions of the tendon previously under tension or previously subjected to pressure. There was an increase in the GAG content in the original tension transmitting region. Initially this was due to increased hyaluronic acid and chondroitin sulfate content during the early remodeling phase. Later when tension was restored to the translocated tendon, the content of these two GAG decreased to normal values while the high overall GAG concentration was maintained by increased amounts of dermatan sulfate. Finally the dermatan sulfate content and the total GAG content returned to normal values.The original pressure bearing region showed a rapid loss of total GAG. This was mainly due to a loss of chondroitin sulfate component, and eventually the region showed a GAG composition similar to that of normal tension transmitting tendo... |
| Databáze: | OpenAIRE |
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