The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion

Autor: Marat V. Ezhov, Angela Pirillo, Lars Ellegård, Andrea Poli, Günter Silbernagel, Olivier S. Descamps, György Paragh, Demosthenes B. Panagiotakos, Alberico L. Catapano, Maciej Banach, Daniel Pella, Michal Vrablík, Zlatko Fras, Petri T. Kovanen, Bernhard Föger, Eric Bruckert, Željko Reiner, Winfried März, Margus Viigimaa, Gustavs Latkovskis
Přispěvatelé: UCL - (SLuc) Service de pathologie cardiovasculaire, Medical University of Łódź (MUL), University of Zielona Góra, Institut E3M [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Sorbonne Université (SU), Cliniques Universitaires Saint-Luc [Bruxelles], Sahlgrenska Academy at University of Gothenburg [Göteborg], Innsbruck Medical University [Austria] (IMU), University of Ljubljana, University of Latvia (LU), Medical University Graz, University of Heidelberg, Medical Faculty, Harokopio University of Athens, University of Debrecen, Pavol Jozef Šafárik University, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), University of Zagreb, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Berlin Institute of Health (BIH), German Center for Cardiovascular Research (DZHK), Tallinn University of Technology (TTÜ), Charles University [Prague] (CU), University of Milan, Gestionnaire, Hal Sorbonne Université, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), University of Debrecen Egyetem [Debrecen], Università degli Studi di Milano = University of Milan (UNIMI)
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Gastrointestinal Diseases
[SDV]Life Sciences [q-bio]
Hypercholesterolemia
Self Medication
030204 cardiovascular system & hematology
Pharmacology
03 medical and health sciences
Food-Drug Interactions
0302 clinical medicine
Plasma cholesterol
Biotransformation
Double-Blind Method
Chinese traditional
Internal Medicine
Red yeast rice
Medicine
Cytochrome P-450 CYP3A
Humans
Multicenter Studies as Topic
Prodrugs
030212 general & internal medicine
Lovastatin
Musculoskeletal Diseases
Medicine
Chinese Traditional

Expert Testimony
ComputingMilieux_MISCELLANEOUS
Randomized Controlled Trials as Topic
Biological Products
Clinical Trials as Topic
Molecular Structure
Ryanodine receptor
business.industry
General Medicine
3. Good health
Cholesterol blood
[SDV] Life Sciences [q-bio]
Cholesterol
Cardiovascular Diseases
Expert opinion
Dietary Supplements
lipids (amino acids
peptides
and proteins)

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cardiology and Cardiovascular Medicine
business
Zdroj: Atherosclerosis. Supplements, Vol. 39, p. e1-e8 (2019)
''Atherosclerosis Supplements''
''Atherosclerosis Supplements'', 2019, ⟨10.1016/j.atherosclerosissup.2019.08.023⟩
DOI: 10.1016/j.atherosclerosissup.2019.08.023⟩
Popis: 1. Preamble : Hypercholesterolemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD) [1]. Increased levels of low density lipoprotein cholesterol (LDL-C) are associated with an increased risk of coronary heart disease (CHD) and many clinical trials have shown that reducing LDL-C levels significantly reduced the CHD and CVD risk [[2], [3], [4], [5]]. Thus LDL-C-lowering is the main approach for the management of cardiovascular disease. Current guidelines suggest LDL-C levels targets based on the individual CV risk; such targets can be achieved by several means, which include both lifestyle changes and pharmacological approaches [6], with statins being the cornerstone of cardiovascular prevention. [...]
Databáze: OpenAIRE