Feline ischemic myelopathy and encephalopathy secondary to hyaline arteriopathy in five cats

Autor: Helena Rylander, Viktor Palus, Abby Caine, Brian A. Summers, Chad West, Joshua Gehrke, Howard Steinberg, Taryn Donovan, Giunio Bruto Cherubini, Philip R Fox, Salih Eminaga
Rok vydání: 2014
Předmět:
Zdroj: Journal of feline medicine and surgery. 16(10)
ISSN: 1532-2750
Popis: Five cats presented with acute-onset neurological signs. Magnetic resonance imaging in four cats showed a T2-weighted hyperintense spinal cord lesion that was mildly contrast-enhancing in three cats. Owing to inflammatory cerebrospinal fluid changes three cats were treated with immunosuppression. One cat was treated with antibiotics. All cats improved initially, but were eventually euthanased owing to the recurrence of neurological signs. Histopathology in all cats showed hyaline degeneration of the ventral spinal artery, basilar artery or associated branches with aneurysmal dilation, thrombosis and ischemic degeneration and necrosis of the spinal cord and brain. Two cats also had similar vascular changes in meningeal vessels. Vascular hyaline degeneration resulting in vascular aneurysmal dilation and thrombosis should be a differential diagnosis in cats presenting with acute central nervous system signs.
Databáze: OpenAIRE