Postnatal physiological changes in electrical activity of the diaphragm in extremely preterm infants

Autor: Kazuko Wada, Shinya Hirano, Eriko Iwasaki, Narutaka Mochizuki, Kazue Morikawa, Masatoshi Nozaki, Katsuya Hirata
Rok vydání: 2020
Předmět:
Zdroj: Pediatric pulmonologyREFERENCES. 55(8)
ISSN: 1099-0496
Popis: OBJECTIVES This study aimed to describe postnatal physiological changes in maximum values of peak electrical activity of the diaphragm (Edi) in extremely preterm infants during the preterm period. WORKING HYPOTHESIS The amplitude and frequency of neural sigh are different at each postmenstrual age in extremely preterm infants. STUDY DESIGN A retrospective, observational study. PATIENT-SUBJECT SELECTION Edi values were evaluated in 14 extremely preterm infants with neurally-adjusted ventilatory assist. METHODOLOGY Data of Edi peak and Edi minimum were collected from a ventilator. Edi-sigh was defined as the Edi peak value that was more than twice as large as the median Edi peak at each postmenstrual week in each patient. The frequency of Edi-sigh, and median values of Edi-sigh, Edi peak, and Edi minimum were evaluated at each postmenstrual week. The Jonckheere-Terpstra test was used to analyze the trend between postmenstrual weeks and Edi values. RESULTS From 26 to 35 postmenstrual weeks, the number of Edi-sighs per hour significantly increased as postmenstrual weeks increased (P
Databáze: OpenAIRE