Palliative Radiotherapy for Diffuse Large B-cell Lymphoma
| Autor: | Joshua Jones, Ima Paydar, Antony I. Koroulakis, G. Kurtz, John P. Plastaras, Jonathan Baron, Elise A. Chong, Yolanda D. Tseng, Amit Maity, Sriram Venigalla, Christopher M. Wright, Michael J. LaRiviere, Pranshu Mohindra |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Oncology Cancer Research medicine.medical_specialty medicine.medical_treatment 03 medical and health sciences 0302 clinical medicine Palliative radiotherapy hemic and lymphatic diseases Internal medicine medicine Humans Curative intent business.industry Palliative Care Treatment options Hematology medicine.disease Progression-Free Survival Lymphoma Radiation therapy 030104 developmental biology 030220 oncology & carcinogenesis Lymphoma Large B-Cell Diffuse business Diffuse large B-cell lymphoma |
| Zdroj: | Clinical Lymphoma Myeloma and Leukemia. 21:650-658 |
| ISSN: | 2152-2650 |
| DOI: | 10.1016/j.clml.2021.05.007 |
| Popis: | Recent improvements in chemoimmunotherapies, targeted agents, hematopoietic stem cell transplants, and cellular therapies have revolutionized treatment paradigms for patients with diffuse large B-cell lymphoma (DLBCL). Even in the relapsed or refractory setting, contemporary treatment options are delivered with curative intent and can lead to lasting remissions. Although such therapies have improved overall outcomes, they have increasingly led to a wide variety of presentations of recurrent tumors in need of palliation. Here, we review the use of radiotherapy (RT) in the palliation of DLBCL. We draw particular attention to the evolving role for hypofractionated RT and low-dose RT for DLBCL. We review the available literature on these topics and focus on commonly encountered clinical scenarios. |
| Databáze: | OpenAIRE |
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