First-pass processing of value cues in the ventral visual pathway
| Autor: | Charles E. Connor, Dennis Sasikumar, Veit Stuphorn, Erik E. Emeric |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Prefrontal Cortex Stimulus (physiology) Biology General Biochemistry Genetics and Molecular Biology Article Visual processing 03 medical and health sciences Microelectrode recording 0302 clinical medicine Reward Attentional modulation Reaction Time Animals Attention Visual Pathways Prefrontal cortex Sensory cue Vision Ocular First pass Cerebral Cortex Neurons Macaca mulatta 030104 developmental biology Pattern Recognition Visual Visual Perception Female Cues General Agricultural and Biological Sciences Neuroscience 030217 neurology & neurosurgery Photic Stimulation |
| Popis: | Summary Real-world value often depends on subtle, continuously variable visual cues specific to particular object categories, like the tailoring of a suit, the condition of an automobile, or the construction of a house. Here, we used microelectrode recording in behaving monkeys to test two possible mechanisms for category-specific value-cue processing: (1) previous findings suggest that prefrontal cortex (PFC) identifies object categories, and based on category identity, PFC could use top-down attentional modulation to enhance visual processing of category-specific value cues, providing signals to PFC for calculating value, and (2) a faster mechanism would be first-pass visual processing of category-specific value cues, immediately providing the necessary visual information to PFC. This, however, would require learned mechanisms for processing the appropriate cues in a given object category. To test these hypotheses, we trained monkeys to discriminate value in four letter-like stimulus categories. Each category had a different, continuously variable shape cue that signified value (liquid reward amount) as well as other cues that were irrelevant. Monkeys chose between stimuli of different reward values. Consistent with the first-pass hypothesis, we found early signals for category-specific value cues in area TE (the final stage in monkey ventral visual pathway) beginning 81 ms after stimulus onset—essentially at the start of TE responses. Task-related activity emerged in lateral PFC approximately 40 ms later and consisted mainly of category-invariant value tuning. Our results show that, for familiar, behaviorally relevant object categories, high-level ventral pathway cortex can implement rapid, first-pass processing of category-specific value cues. |
| Databáze: | OpenAIRE |
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