Development and Longevity: Cellular and Molecular Determinants - A Mini-Review

Autor:	Antonello Lorenzini, Silvia Marchionni, Christian Sell
Přispěvatelé:	Marchionni S., Sell C., Lorenzini A.
Rok vydání:	2019
Předmět:	Senescence Aging Growth rate DNA damage media_common.quotation_subject Caloric restriction Longevity Biology Development Telomere Mini review Rate of development Evolutionary biology IGF-1 Animals Humans Geriatrics and Gerontology Organism Cellular Senescence media_common
Zdroj:	Gerontology. 66(3)
ISSN:	1423-0003
Popis:	Across species, development and longevity are tightly linked. We discuss the relevant literature and suggest that the root for this stringent relationship is the rate of development. The basis for the relationship between rate of development and longevity lies in adaptations that have occurred through evolution at multiple levels of biological complexity: organism, organ, cellular, and molecular. Thus, the analysis of the relationship is of interest for multiple fields of biology.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d60a93277c9bb9be74361809fe808d1 https://pubmed.ncbi.nlm.nih.gov/32036369 Zobrazit plný text záznamu