Cord blood ischemia-modified albumin: Is it associated with abnormal Doppler findings in complicated pregnancies and predictive of perinatal asphyxia?
| Autor: | Gul Huray Islekel, Serkan Guclu, Abdullah Kumral, Emre Okyay, Gamze Demirel, Pinar Gencpinar, Nuray Duman, Serife Suna Oguz, Melis Kant, Hasan Ozkan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Cerebral arteries Serum Albumin Human Doppler imaging Ultrasonography Prenatal Young Adult Pregnancy Medicine Humans Prospective Studies Prospective cohort study Serum Albumin Asphyxia Neonatorum business.industry Obstetrics Albumin Infant Newborn Obstetrics and Gynecology Liter Ultrasonography Doppler medicine.disease Perinatal asphyxia Pregnancy Complications Cord blood Case-Control Studies Female business Biomarkers |
| Popis: | Aim To evaluate the significance of the cord blood ischemia-modified albumin (IMA) level as a diagnostic marker for perinatal asphyxia and to determine the associations of IMA levels with the complexity of pregnancy and abnormal Doppler findings, regardless of perinatal asphyxia. Methods This prospective study included 169 newborns, sixteen of whom had perinatal asphyxia and 33 who were from complicated pregnancies. Doppler measurements were obtained from the uterine, umbilical and middle cerebral arteries, and the cerebro/placental ratio (C/P). IMA was measured by means of commercially available ELISA kits and was expressed as picomoles per milliliter. Results Ischemia-modified albumin levels were significantly higher in neonates of complicated pregnancies as compared to uncomplicated pregnancies (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|