Secreted pectin monooxygenases drive plant infection by pathogenic oomycetes
| Autor: | Michael Csukai, Paul H. Walton, Lydia Welsh, Anna O. Avrova, Peter J. Lindley, Neil C. Bruce, Bernard Henrissat, Julie Squires, Gideon J. Davies, Stephen C. Whisson, Simon J. McQueen-Mason, Federico Sabbadin, Saioa Urresti |
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| Přispěvatelé: | Architecture et fonction des macromolécules biologiques (AFMB), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University of York [York, UK], Instituto Biofisika, Universidad del Pais Vasco / Euskal Herriko Unibertsitatea [Espagne] (UPV/EHU)-Consejo Superior de Investigaciones Científicas [Madrid] (CSIC) |
| Rok vydání: | 2021 |
| Předmět: |
Models
Molecular MESH: Oxidation-Reduction 0106 biological sciences Protein Conformation [SDV]Life Sciences [q-bio] 01 natural sciences Mixed Function Oxygenases MESH: Protein Conformation MESH: Plant Diseases Solanum lycopersicum MESH: Lycopersicon esculentum Pathogen 2. Zero hunger Oomycete 0303 health sciences Multidisciplinary biology food and beverages MESH: Mixed Function Oxygenases MESH: Copper MESH: Plant Leaves Lytic cycle Phytophthora infestans Pectins MESH: Protein Domains Oxidation-Reduction MESH: Models Molecular Virulence Factors Virulence MESH: Solanum tuberosum Microbiology Cell wall 03 medical and health sciences Protein Domains Polysaccharides Gene Plant Diseases Solanum tuberosum MESH: Virulence Factors 030304 developmental biology Host (biology) fungi biology.organism_classification Plant Leaves MESH: Polysaccharides MESH: Phytophthora infestans Copper MESH: Pectins 010606 plant biology & botany |
| Zdroj: | Science Science, American Association for the Advancement of Science, 2021, 373 (6556), pp.774-779. ⟨10.1126/science.abj1342⟩ Science, 2021, 373 (6556), pp.774-779. ⟨10.1126/science.abj1342⟩ |
| ISSN: | 1095-9203 0036-8075 |
| DOI: | 10.1126/science.abj1342 |
| Popis: | Potato pectin falls to Phytophthora Phytophthora infestans is a plant oomycete pathogen that drove the potato famines of the 1800s and continues to afflict potato fields today. The polysaccharide pectin makes up about a third of the cell wall in potatoes. Sabbadin et al . identified a family of lytic polysaccharide monooxygenases (LMPOs) that cleave pectin and are upregulated in P. infestans during infection. Silencing the relevant LMPO gene successfully inhibited P. infestans infections. These findings open doors for disease intervention targets and for biotech applications. —PJH |
| Databáze: | OpenAIRE |
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