Pharmacokinetic/pharmacodynamic analysis of linezolid in critically ill patients with severe sepsis treated with renal replacement therapy
| Autor: | A. Martín López, A Soraluce Olañeta, A Rodríguez Gascón, A Isla Ruiz, F Muñoyerro González, S. Castaño Ávila, FJ Maynar Moliner, H. Barrasa González, F. Fonseca San Miguel, A Rodríguez Oviedo, JA Sánchez Izquierdo |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
education.field_of_study Critically ill business.industry medicine.medical_treatment Population Critical Care and Intensive Care Medicine chemistry.chemical_compound Pharmacokinetics chemistry Internal medicine Pharmacodynamics Linezolid Poster Presentation medicine Renal replacement therapy Dosing Intensive care medicine education business Severe sepsis |
| Zdroj: | Intensive Care Medicine Experimental |
| ISSN: | 2197-425X |
| Popis: | Pharmacokinetic (PK) of drugs in critically ill patients could vary from the general population. The pharmacokinetics of linezolid presents a high variability. Patients undergoing renal replacement therapy (RRT) could present lower linezolid concentration than expected. The pharmacokinetic/pharmacodynamic analysis (PK/ PD) is a useful tool to optimize dosing regimens of antibiotic therapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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