Malignant melanoma of the male urethra with increased 5‐S‐cysteinyldopa: A case report
| Autor: | Naotaka Fukui, Yasuyuki Sakai, Yusuke Aoki, Yuki Nakamura, Takahiko Soma, Yukio Kageyama |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Urology malignant melanoma Case Report Reference range Case Reports lcsh:RC870-923 Melanin penis 5‐S‐cysteinyldopa male Biopsy medicine Dysuria Penectomy medicine.diagnostic_test business.industry Melanoma medicine.disease lcsh:Diseases of the genitourinary system. Urology medicine.anatomical_structure Urethra medicine.symptom urethra business Penis |
| Zdroj: | IJU Case Reports, Vol 2, Iss 4, Pp 215-217 (2019) IJU Case Reports |
| Popis: | Introduction We herein present a case of malignant melanoma of the male urethra with an increased serum 5-S-cysteinyldopa concentration. Case presentation A 77-year-old man visited our hospital complaining dysuria and a dark brown mass protruding from the external urethral meatus. His serum 5-S-cysteinyldopa concentration was elevated beyond the upper limit of the reference range. Biopsy of the tumor was performed, and the histological diagnosis was malignant melanoma. He underwent total penectomy, and the serum 5-S-cysteinyldopa concentration was normalized. He remained alive without evidence of locoregional recurrence or distant metastases for 6 months after surgery. Conclusion Malignant melanoma of the male urethra is uncommon. The prognosis is favorable if it is detected in its early stages. This case report suggests that measurement of the serum concentration of 5-S-cysteinyldopa, a melanin metabolite, is useful for early diagnosis of male urethral melanoma. |
| Databáze: | OpenAIRE |
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