Risk factors for dementia onset in older adults with metastatic renal cell carcinoma

Autor: Samuel Miller, Lauren Wilson, Melissa Greiner, Jessica Pritchard, Tian Zhang, Deborah Kaye, Harvey Cohen, Michaela Dinan
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Innovation in Aging
ISSN: 2399-5300
2007-2015
Popis: Renal dysfunction is a driver of dementia. It is also associated with renal cell carcinoma, possibly the result of the tumor itself or from cancer treatment. This study evaluates metastatic renal cell carcinoma (mRCC) as a risk factor for developing mild cognitive impairment or dementia (MCI/D) as well as the impact of RCC-directed therapies on the development of MCI/D. We identified all patients diagnosed with mRCC in SEER-Medicare from 2007-2015. The main outcome was incident MCI/D within one year of mRCC diagnosis or cohort entry. Exclusion criteria included age
Databáze: OpenAIRE