Persistence of Porphyromonas gingivalis is a negative predictor in patients with moderate to severe periodontitis after nonsurgical periodontal therapy
| Autor: | Sigrun Eick, Martin Kramesberger, Karolin Vollroth, Christoph A. Ramseier, Holger Jentsch, Anton Sculean, Ayse Mathey, Walter Bürgin |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Dentistry 610 Medicine & health Logistic regression Gastroenterology Persistence (computer science) 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Periodontitis General Dentistry Porphyromonas gingivalis Aged biology business.industry Treponema denticola Gingival Crevicular Fluid 030206 dentistry Middle Aged medicine.disease biology.organism_classification Chronic periodontitis 3. Good health 030104 developmental biology Biofilms Female Analysis of variance Calprotectin business Biomarkers |
| Zdroj: | Eick, Sigrun; Mathey, Ayse; Vollroth, Karolin; Kramesberger, Martin; Bürgin, Walter; Sculean, Anton; Ramseier, Christoph; Jentsch, Holger (2017). Persistence of Porphyromonas gingivalis is a negative predictor in patients with moderate to severe periodontitis after nonsurgical periodontal therapy. Clinical oral investigations, 21(2), pp. 665-674. Springer-Verlag 10.1007/s00784-016-1933-x |
| ISSN: | 1436-3771 1432-6981 |
| DOI: | 10.1007/s00784-016-1933-x |
| Popis: | OBJECTIVES The aim of this study was to evaluate the quality of prediction for stable results after nonsurgical periodontal therapy by several microbiological variables of the subgingival biofilm and biomarkers of gingival crevicular fluid or oral lavage. MATERIAL AND METHODS Forty-six individuals with moderate or severe chronic periodontitis receiving nonsurgical periodontal therapy were monitored for clinical variables, selected microorganisms, and biomarkers at baseline and 3 and 6 months thereafter. Logistic regression analysis and general linear model (GLM) were applied for analysis of variance and covariance. RESULTS At 6 months, 20 patients showed a high response (HR) to treatment (at least 60 % of reduction of numbers of sites with PD >4 mm), whereas 26 did not (low response, LR). All clinical variables were significantly improved at 3 and 6 months within each group (p |
| Databáze: | OpenAIRE |
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