Legionella pneumophila in bronchoalveolar lavage samples of patients suffering from severe respiratory infections: Role of age, sex and history of smoking in the prevalence of bacterium
| Autor: | Forouzan Khedri, Abbas Doosti, Fatemeh Alaei Faradonbeh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty prevalence Prevalence lcsh:Medicine Comorbidity bronchoalveolar lavages Iran Legionella pneumophila Bronchoalveolar Lavage Polymerase Chain Reaction Severity of Illness Index respiratory infections Internal medicine medicine Humans risk factors Acute respiratory tract infection Lung Respiratory Tract Infections Aged Legionellosis Respiratory tract infections biology medicine.diagnostic_test business.industry Incidence (epidemiology) Mortality rate Smoking lcsh:R General Medicine Middle Aged biology.organism_classification bacterial infections and mycoses respiratory tract diseases medicine.anatomical_structure Bronchoalveolar lavage Immunology bacteria Female business Bronchoalveolar Lavage Fluid |
| Zdroj: | Srpski Arhiv za Celokupno Lekarstvo, Vol 143, Iss 5-6, Pp 274-278 (2015) |
| ISSN: | 0370-8179 |
| Popis: | Introduction. Legionella pneumophila is the most commonly detected cause of legionellosis, which is an acute respiratory tract infection with high morbidity and mortality rates. Objective. The aim of this study was to investigate the prevalence rate of L. pneumophila in bronchoalveolar lavages and study the role of sex, age and history of smoking as risk factors for susceptibility to the bacterium. Methods. One hundred bronchoalveolar lavage samples were collected from the Iranian health centers and immediately transferred to laboratory. The samples were cultured and those that were L. pneumophila positive were subjected to PCR method with respect to the 16S rRNA gene. Results. Twelve out of 100 samples were positive for L. pneumophila (12%). Patients older than 70 years had the highest incidence of L. pneumophila (17.77%). Prevalence of L. pneumophila in male and female patients was 14.81% and 8.69%, respectively. Total incidence of L. pneumophila in patients with and without history of smoking was 18% and 6%, respectively. There were significant differences in the incidence of bacterium between groups of our study. Conclusion. Sex, age and history of smoking are predominant risk factors for the occurrence of L. pneumophila. However, more studies should be undertaken to confirm these results. |
| Databáze: | OpenAIRE |
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