Vitamin D status in diabetic Egyptian children and adolescents: a case–control study
| Autor: | Alshaymaa Ahmed Ali, Safaa H. Saleh, Sanaa M. Abdelsalam, Seham F. Azab, Wafaa F Elsaeed, Asmaa Esh |
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| Rok vydání: | 2013 |
| Předmět: |
Blood Glucose
Male medicine.medical_specialty Adolescent endocrine system diseases Parathyroid hormone Comorbidity Risk Assessment Statistics Nonparametric vitamin D deficiency Diabetic Age Distribution Insulin resistance Reference Values Internal medicine Diabetes mellitus medicine Vitamin D and neurology Humans Insulin Vitamin D Sex Distribution Child Children Developing Countries Hyperparathyroidism business.industry Research Incidence Incidence (epidemiology) Case-control study Vitamin D Deficiency medicine.disease Diabetes Mellitus Type 1 Treatment Outcome Endocrinology Case-Control Studies Egypt Female business |
| Zdroj: | Italian Journal of Pediatrics |
| ISSN: | 1824-7288 |
| Popis: | Background Recently, studies suggesting that vitamin D deficiency correlates with the severity and frequency of Type 1 (insulin-dependent) diabetes mellitus (T1DM) and that vitamin D supplementation reduces the risk of developing T1DM have been reported. Objective In this study, we aimed to assess vitamin D status in Egyptian children and adolescents with T1DM. Methods This was a case–control study including 80 T1DM diagnosed cases aged 6 to 16 years and 40 healthy children with comparable age and gender as the control group. For all subjects, serum 25 (OH) D levels were measured by ELISA, Serum parathyroid hormone (PTH) and serum insulin were measured by an electrochemiluminesce immunoassay. Serum glucose, Glycosylated hemoglobin (HbA1c) levels and homeostasis model assessment of insulin resistance (HOMA-IR) were also assessed. Results Compared to the control group, serum vitamin D levels were not significantly lower in diabetic subjects (24.7 ± 5.6 vs 26.5 ± 4.8 ng/ml; P > 0.05). Among diabetic cases 44(55%) were vitamin D deficient; meanwhile 36(45%) cases had normal vitamin D level (P |
| Databáze: | OpenAIRE |
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