Treatment of rectovaginal fistula by magnetic compression
| Autor: | Haohua Wang, Xin Qi, Zhan-Fei She, Yi Lv, Bin Xiao, Huan Yang, Yu-Liang Zou, Liang Wang, Xiaopeng Yan, Feng Ma, Aihua Shi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
medicine.medical_specialty Swine Urology Rectum Anal Canal Anastomosis 03 medical and health sciences 0302 clinical medicine Recurrence Medicine Effective treatment Animals Humans Surgical repair Analysis of Variance Wound Healing Sutures business.industry Rectovaginal Fistula Obstetrics and Gynecology Pig model Compression procedure Equipment Design medicine.disease Sutureless Surgical Procedures Surgery medicine.anatomical_structure Treatment Outcome Rectovaginal fistula 030220 oncology & carcinogenesis Case-Control Studies Models Animal Vagina Magnets 030211 gastroenterology & hepatology Female business |
| Zdroj: | International urogynecology journal. 28(2) |
| ISSN: | 1433-3023 |
| Popis: | Rectovaginal fistula (RVF) is an abnormal epithelium-lined connection between the rectum and vagina. The primary effective treatment is surgical repair, but recurrence remains a challenge. Magnetic compression anastomosis (MCA), an alternative to suturing, has been developed to generate an anastomosis between various hollow viscera. We hypothesized that the MCA approach could be used to treat RVF. We designed a novel MCA device for RVF treatment and evaluated the magnetic compression procedure in a RVF pig model in comparison with the traditional suturing procedure. Following satisfactory outcomes, we also applied the MCA procedure to a human patient with recurrent RVF. The MCA device was designed based on the anatomical characteristics of the pig vagina and previous literature. The pig RVF model were established surgically (n = 12), and compression and control groups were each treated. The data were analyzed by one-way analysis of variance. qqExcept in one animal in each group, the RVF site was smooth and healing was complete. Histological analysis confirmed complete healing of the RVF with high histological continuity to neighboring tissues. The compression procedure applied to our patient with RVF was successful. The patient recovered quickly without complications, and RVF did not recur during a 15-month follow-up. From this preliminary investigation, MCA using our novel device appears to be a safe, simple, and effective nonsurgical procedure for the treatment of RVF. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink