Enhanced Antioxidant, Antiviral, and Anticancer Activities of the Extract of Fermented Egyptian Rice Bran Complexed with Hydroxypropyl-β-cyclodextrin

Autor: Sherif Ashraf Fahmy, Khaled A. Nematallah, Noha Khalil Mahdy, Hesham I. El-Askary, Meselhy Ragab Meselhy, Hassan Mohamed El-Said Azzazy
Rok vydání: 2022
Předmět:
Zdroj: ACS omega. 7(23)
ISSN: 2470-1343
Popis: Egyptian rice bran was fermented with baker's yeast, and released phenolics were extracted with aqueous methanol to give fermented rice bran extract (FRBE). The analysis of the FRBE with ultra-performance liquid chromatography-electrospray ionization-tandem mass spectrometry revealed 21 compounds, mainly phenolic acids and flavonoids. The FRBE was then complexed with (2-hydroxypropyl)-β-cyclodextrin (HPβCD) via noncovalent host-guest inclusion complexation using the thin-film hydration technique to improve the hydrophilicity and bioactivity of the FRBE. The formation of the inclusion complex was confirmed using HPLC
Databáze: OpenAIRE