Functional activity of isolated perfused rat liver depends on medium composition
| Autor: | A. P. Rupenko, O. V. Kruglik, I. I. Morgulis |
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| Rok vydání: | 2008 |
| Předmět: |
Oxygen transport
General Medicine Oxygenation Metabolism Biology General Biochemistry Genetics and Molecular Biology Culture Media Rats Perfusion Tissue Culture Techniques Oxygen Consumption Liver Biochemistry Rat liver Animals Functional activity Female Composition (visual arts) Liver function Rats Wistar Liver Circulation |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 146:107-110 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-008-0219-y |
| Popis: | It is convenient to study liver function and metabolism on the model of isolated perfused organ. The results of the present study indicate that viability and metabolic activity of the organ largely depend on the composition of the medium. Under conditions of isolated perfusion, the known pathway of oxygen transport through capillary filtration is supplemented by oxygen delivery to cells through the organ surface making an important contribution to liver oxygenation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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