Image-guided, navigation-assisted Relieva Stratus MicroFlow Spacer insertion into the ethmoid sinus
Autor: | Rami Taulu, Argyro J. Bizaki, Jura Numminen, Markus Rautiainen |
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Rok vydání: | 2014 |
Předmět: |
medicine.medical_specialty
Ethmoid Sinusitis Triamcinolone acetonide Topical Corticosteroid Therapy medicine.medical_treatment Anti-Inflammatory Agents Triamcinolone Acetonide Imaging Three-Dimensional Ethmoid Sinus Ethmoid sinus otorhinolaryngologic diseases medicine Humans Fluoroscopy medicine.diagnostic_test business.industry Stent Drug-Eluting Stents Endoscopy General Medicine eye diseases Surgery medicine.anatomical_structure Surgery Computer-Assisted Otorhinolaryngology Implant business medicine.drug |
Zdroj: | European Archives of Oto-Rhino-Laryngology. 272:2335-2340 |
ISSN: | 1434-4726 0937-4477 |
DOI: | 10.1007/s00405-014-3334-6 |
Popis: | Anatomical complexity presents the main challenge in the administration of topical corticosteroid therapy to the paranasal sinus mucosa. This often leads to suboptimal drug delivery due to low concentrations of the therapeutic agent to the intended target area. The Relieva Stratus™ MicroFlow Spacer (Relieva Stratus) is a drug-eluting stent that is temporarily implanted into the ethmoid sinus. The reservoir of the stent is filled with triamcinolone acetonide, which is then slowly released from the device into the ethmoid sinus mucosa. The Relieva Stratus provides local and targeted delivery of the anti-inflammatory agent to the diseased mucosa. This minimally invasive implant is an option when treating ethmoid sinusitis. From January 2011 to November 2013, a total of 52 Relieva Stratus implantations into the ethmoidal cells were performed at the Department of Ear and Oral Diseases at Tampere University Hospital, Finland. C-arm fluoroscopy guidance was employed for 26 sinuses (13 patients) and optical image-guided surgery (IGS)-assisted insertions were performed on another 26 sinuses (13 patients). The accuracy of fluoroscopic insertion is not optimal, but this method is accurate enough to prevent the violation of the skull base and lamina papyracea. IGS enables the precise treatment of the diseased cells. From a technical perspective, IGS-guided insertion is a faster, safer and more exact procedure that guarantees the optimal positioning and efficacy of the implant. Moreover, IGS guidance does not entail the use of ionizing radiation. |
Databáze: | OpenAIRE |
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