Rodents are carriers of Clostridioides difficile strains similar to those isolated from piglets
Autor: | Roberto Maurício Carvalho Guedes, Rodrigo Otávio Silveira Silva, Carlos Augusto de Oliveira, Francisco Carlos Faria Lobato, Fabrice Poncet, Dominique S. Blanc, Michelle de Paula Gabardo |
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Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Genotype Swine animal diseases 030106 microbiology Bacterial Toxins Rodentia Biology Microbiology Immunoenzyme Techniques 03 medical and health sciences Feces Animals Typing Intestinal contents Disease Reservoirs Swine Diseases Bacteriological Techniques Clostridioides difficile Clostridium difficile Infectious Diseases Immunoenzyme techniques Carrier State Clostridium Infections Multilocus sequence typing Clostridioides Multilocus Sequence Typing |
Zdroj: | Anaerobe. 51 |
ISSN: | 1095-8274 |
Popis: | Features of Clostridioides difficile transmission in swine and the role of rodents as C. difficile reservoir are not clear. To investigate if rodents can carry strains of C. difficile that are genetically similar to those isolated from swine, 97 fecal samples from neonatal piglets and 41 intestinal contents from rodents were collected in two farms. All samples were subjected to C. difficile culture and the presence of A/B toxins in piglet feces were accessed by commercial enzyme imunoassay (EIA). C. difficile isolates were typed by double- (DLST) and multi-locus sequence typing (MLST). C. difficile was isolated from 15.5% of piglets and 31.7% of rodents. Most isolates were identified as DLST type 4-4 and 17-5 (both are ST11), which were found in both rodents and piglets. Results of this study suggested that rodents may have a role on the transmission and spread of C. difficile strains to swine. |
Databáze: | OpenAIRE |
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