Carotid dissection with and without ischemic events: Local symptoms and cerebral artery findings
Autor: | Marcel Arnold, Gerhard Schroth, M. Mosso, Matthias Sturzenegger, A. Studer, Ralf W. Baumgartner, I. Baumgartner, B. Schuknecht, F. Gönner |
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Rok vydání: | 2001 |
Předmět: |
Adult
Male medicine.medical_specialty Horner Syndrome Adolescent ICAD Cerebral arteries Ischemia Horner syndrome Carotid Artery Internal Dissection Constriction Pathologic Statistics Nonparametric Brain Ischemia Risk Factors Internal medicine medicine Humans Prospective Studies Aged Internal carotid artery dissection business.industry Vascular disease Cerebral Arteries Middle Aged medicine.disease Cranial Nerve Diseases Surgery Stenosis medicine.anatomical_structure Cardiology Cerebral Arterial Diseases Neurology (clinical) business Artery |
Zdroj: | Neurology. 57:827-832 |
ISSN: | 1526-632X 0028-3878 |
Popis: | To study whether spontaneous dissections of the cervical internal carotid artery dissection (ICAD) with and without ischemia of the brain or retina differ in the prevalence of vascular risk factors, local neurologic signs and symptoms, and stenoses and occlusions of the cerebral arteries.The authors prospectively studied 181 consecutive patients with 200 ICAD. Diagnosis was based on ultrasonography and MRI or catheter angiography. Vascular risk factors, presenting local (headache, neck pain, Horner syndrome, pulsatile tinnitus, cranial nerve palsy on the side of the ICAD) and ischemic signs and symptoms, and ultrasonographic findings in the carotid and basal cerebral arteries were evaluated.ICAD with ischemic events (n = 145) had a higher prevalence of hypercholesterolemia (p0.05),80% stenoses and occlusions of the ICA (p0.0001), and intracranial obstructions (p0.001). ICAD without ischemic events (n = 55) had a higher prevalence of Horner syndrome (p0.001), cranial nerve palsy (p0.01), and normal ICA findings (p0.0001).These data suggest that ICAD causing high-grade stenosis and occlusion are more likely to lead to intracranial obstructions and cerebral or retinal ischemic events. Conversely, ICAD without luminal narrowing cause more local signs and symptoms. |
Databáze: | OpenAIRE |
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