Physical activity and lung cancer risk in men and women
| Autor: | Vikki Ho, Anita Koushik, Michal Abrahamowicz, Coraline Danieli, Javier Pintos, Lise Gauvin, Jack Siemiatycki, Robert Bourbonnais, Marie-Élise Parent, Lesley Richardson |
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| Přispěvatelé: | Centre Hospitalier de l'Université de Montréal (CHUM), Université de Montréal (UdeM), Institut Armand Frappier (INRS-IAF), Institut National de la Recherche Scientifique [Québec] (INRS)-Réseau International des Instituts Pasteur (RIIP), Department of Epidemiology, Biostatistics and Occupational Health [Montréal], McGill University = Université McGill [Montréal, Canada] |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Canada Histology [SDV]Life Sciences [q-bio] Population Logistic regression Motor activity 03 medical and health sciences 0302 clinical medicine Risk Factors Lung neoplasms Epidemiology medicine Humans 030212 general & internal medicine Lung cancer education Life Style Exercise Aged education.field_of_study Occupation business.industry Smoking Case-control study Odds ratio Middle Aged Protective Factors medicine.disease Confidence interval Case–control studies Oncology 030220 oncology & carcinogenesis Case-Control Studies Physical therapy Recreation Female business Body mass index Demography |
| Zdroj: | Cancer Causes and Control Cancer Causes and Control, Springer Verlag, 2017, 28 (4), pp.309-318. ⟨10.1007/s10552-017-0872-4⟩ |
| ISSN: | 0957-5243 1573-7225 |
| Popis: | International audience; Although evidence has accumulated that recreational physical activities (PA) may reduce lung cancer risk, there is little evidence concerning the possible role of a potentially more important source of PA, namely occupational PA. We investigated both recreational and lifetime occupational PA in relation to lung cancer risk in a population-based case-control study in Montreal, Canada (NCASES = 727; NCONTROLS = 1,351).; Unconditional logistic regression was used to estimate odds ratios (OR), separately for men and women, adjusting for smoking, exposure to occupational carcinogens, and sociodemographic and lifestyle factors.; In both sexes, increasing recreational PA was associated with a lower lung cancer risk (ORMEN = 0.66, 95% confidence interval (CI) 0.47-0.92; ORWOMEN = 0.55, 95% CI 0.34-0.88, comparing the highest versus lowest tertiles). For occupational PA, no association was observed among women, while increasing occupational PA was associated with increased risk among men (ORMEN = 1.96, 95% CI 1.27-3.01). ORs were not modified by occupational lung carcinogen exposure, body mass index, and smoking level; results were similar across lung cancer histological types.; Our results support the previous findings for recreational PA and lung cancer risk. Unexpectedly, our findings suggest a positive association for occupational PA; this requires replication and more detailed investigation. |
| Databáze: | OpenAIRE |
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