Absence of efficacy of oral isotretinoin in hidradenitis suppurativa: a retrospective study based on patients' outcome assessment
| Autor: | Florence Poli, Angèle Soria, Pierre Wolkenstein, Jean Revuz, Florence Canoui-Poitrine, C. Viallette, Germaine Gabison, Florence Pouget |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Administration Oral Dermatology Outcome assessment Severity of Illness Index Treatment failure Surveys and Questionnaires Severity of illness medicine Humans Hidradenitis suppurativa Treatment Failure skin and connective tissue diseases Isotretinoin Acne Retrospective Studies business.industry Retrospective cohort study Oral isotretinoin medicine.disease Hidradenitis Suppurativa Female Dermatologic Agents business medicine.drug |
| Zdroj: | Dermatology (Basel, Switzerland). 218(2) |
| ISSN: | 1421-9832 |
| Popis: | Background: In analogy to acne, oral isotretinoin has been considered in the treatment of hidradenitis suppurativa (HS). Objectives: To assess the efficacy of oral isotretinoin according to patients. Methods: From 1999 to 2006, 358 consecutive HS patients were interviewed and examined. A standardized record of the data was performed for each patient during the first consultation. Patients were questioned regarding the effect of previous treatment with oral isotretinoin: patients had to grade the effect as either ‘improved’, ‘no effect’ or ‘worse’. Results: Fourteen patients (16.1%) declared an improvement, 67 patients (77%) no effect and 6 patients (6.9%) worsening of HS. Conclusion: According to our patients, oral isotretinoin is not effective in the treatment of HS. |
| Databáze: | OpenAIRE |
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