The PEDANT genome database
| Autor: | Matthias Fellenberg, Klaus Heumann, Andreas Volz, Christian Gruber, Kaj Albermann, Hans-Werner Mewes, Christian Wagner, Grigory Kolesov, Birgitta Geier, Andreas Kaps, Gabi Kastenmüller, Martin Mokrejs, Igor Z. Zubrzycki, Dmitrij Frishman, Denis Kosykh |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Saccharomyces cerevisiae Proteins
Sequence analysis Information Storage and Retrieval Sequence Homology Genomics Context (language use) Computational biology Biology Genome Structural genomics Mice Data retrieval Sequence Analysis Protein Gene Duplication Pedant Databases Genetic Protein Interaction Mapping Genetics Animals Humans Protein function prediction Computational Biology Proteins Articles ComputingMethodologies_PATTERNRECOGNITION |
| Zdroj: | Nucleic Acids Research. 31:207-211 |
| ISSN: | 1362-4962 |
| DOI: | 10.1093/nar/gkg005 |
| Popis: | The PEDANT genome database (http://pedant.gsf.de) provides exhaustive automatic analysis of genomic sequences by a large variety of established bioinfor- matics tools through a comprehensive Web-based user interface. One hundred and seventy seven completely sequenced and unfinished genomes have been processed so far, including large eukar- yotic genomes (mouse, human) published recently. In this contribution, we describe the current status of the PEDANT database and novel analytical features added to the PEDANT server in 2002. Those include: (i) integration with the BioRS TM data retrieval system which allows fast text queries, (ii) pre-computed sequence clusters in each complete genome, (iii) a comprehensive set of tools for genome comparison, including genome comparison tables and protein function prediction based on genomic context, and (iv) computation and visualization of protein- protein interaction (PPI) networks based on experi- mental data. The availability of functional and structural predictions for 650 000 genomic proteins in well organized form makes PEDANT a useful resource for both functional and structural genomics. |
| Databáze: | OpenAIRE |
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