Validation of 'Signs of Inflammation in Children that Kill' (SICK) score for immediate non-invasive assessment of severity of illness
| Autor: | Jacob M Puliyel, Jayanti J Rangasami, Anjan Chakrabarty, Vishnubhatla Sreenivas, Ashish Puliyel, Ruth Halstead, David A Green, Mohit Sahni, Manoj Anand Gupta |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Scoring system Severity of Illness Index Age Distribution Cause of Death Severity of illness London Outcome Assessment Health Care Medicine Humans Hospital Mortality Prospective Studies Prospective cohort study Child Cause of death Resource poor Receiver operating characteristic business.industry Research Non invasive lcsh:RJ1-570 Infant Newborn Infant lcsh:Pediatrics Hospitals Pediatric Triage ROC Curve Child Preschool Acute Disease Female Emergencies business |
| Zdroj: | Italian Journal of Pediatrics Italian Journal of Pediatrics, Vol 36, Iss 1, p 35 (2010) |
| ISSN: | 1824-7288 |
| Popis: | Objective To validate the SICK scoring system's ability to differentiate between individuals with higher and lower probabilities of death Method We performed a one year two-centre prospective evaluation of all children aged between one month and 12 years referred to the Paediatric team at St Stephens Hospital in Delhi and admitted to the Paediatric Department at West Middlesex University Hospital in London. We calculated SICK scores at presentation and correlated them with subsequent in-hospital mortality. We used discrimination by areas under receiver operating characteristic (ROC) curves to measure performance. Results We prospectively evaluated 3895 children in Delhi and 1473 children in London. The areas under the ROC curves were 84.8% in Delhi, 81.0% in London and 84.1% (95% CI 77.4 - 90.8%) for combined data. Hosmer-Lemeshow goodness of fit for the combined data was good (Hosmer-Lemeshow Chi-square = 2.13 (p = 0.345). Conclusions We propose the SICK score as a useful triage tool at initial presentation and highlight its particular suitability for resource poor settings. |
| Databáze: | OpenAIRE |
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