Antiepileptic Drug Use Patterns in Suspect Epileptic Dogs Among Neurology and Emergency Specialists
| Autor: | Tessa Meland, Sheila Carrera-Justiz, Gareth J. Buckley |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pediatrics
medicine.medical_specialty Neurology 040301 veterinary sciences Cross-sectional study Initial dose Antiepileptic drug Loading dose Drug Administration Schedule Veterinarians 0403 veterinary science 03 medical and health sciences Epilepsy Dogs Intensive care medicine Animals Dog Diseases Small Animals 030304 developmental biology 0303 health sciences business.industry Data Collection 04 agricultural and veterinary sciences medicine.disease Cross-Sectional Studies Emergency Medicine Anticonvulsants Levetiracetam business medicine.drug |
| Zdroj: | Journal of the American Animal Hospital Association. 55:138-143 |
| ISSN: | 1547-3317 0587-2871 |
| DOI: | 10.5326/jaaha-ms-6795 |
| Popis: | This study used a cross-sectional survey designed to inquire about antiepileptic drug (AED) use in newly diagnosed idiopathic epileptic dogs among board-certified emergency and neurology specialists. Results were obtained from 300 completed surveys by 128 board-certified neurologists and 172 board-certified emergency and critical care (ECC) specialists. Case volume was slightly different between groups, with 36% of neurologists and 18% of ECC specialists managing >50 cases of first-time canine seizure patients yearly. The initial AED of choice was similar between the groups, with 66% of neurologists and 64% of ECC specialists using phenobarbital and 16% of neurologists and 26% of ECC specialists using levetiracetam. Although most respondents gave a loading dose of phenobarbital, roughly one-fourth of neurologists did not load the drug versus 6% of ECC specialists. The total loading dose was similar between respondents (16 mg/kg) but varied in administration protocol. Approximately half of neurologists and nearly two-thirds of ECC specialists gave a higher initial dose of levetiracetam than recommended. Almost all the respondents who gave a higher initial dose of levetiracetam used 60 mg/kg IV once. Understanding the common practices in AED use may promote future discussions regarding best practices in the management of canine idiopathic epilepsy. |
| Databáze: | OpenAIRE |
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