Three‐dimensional analysis of the human pharyngoesophageal sphincter
| Autor: | E. Bradley Strong, Daniel J. Cates, Peter C. Belafsky, Derrick R. Randall |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Models Anatomic medicine.medical_specialty Laryngology 03 medical and health sciences 0302 clinical medicine Cadaver Cricoid cartilage medicine Humans Esophagus 030223 otorhinolaryngology Aged 030304 developmental biology 0303 health sciences business.industry Pharynx Anatomy Esophageal Sphincter Upper Dysphagia body regions medicine.anatomical_structure Otorhinolaryngology Dilator Dilation (morphology) Female medicine.symptom Deglutition Disorders Tomography X-Ray Computed business human activities |
| Zdroj: | The Laryngoscope. 130:2773-2778 |
| ISSN: | 1531-4995 0023-852X |
| DOI: | 10.1002/lary.28450 |
| Popis: | OBJECTIVES Dysfunction of the pharyngoesophageal segment (PES) is a common cause of oropharyngeal dysphagia. Surgical dilation of the PES uses cylindrical dilators that expand radially in a circular shape. Animal studies, however, suggest that the PES is kidney-shaped. The purpose of this investigation was to evaluate the 3D shape of the human PES with a novel casting method. METHODS A platinum-cured liquid silicone polymer was infused under pressure into the upper aerodigestive tract of nine fresh human cadavers to construct 3D casts of the maximally distended PES. Cross-sectional and volumetric analysis were performed using computed tomography and serial sectioning of the models. Canonical variate analysis was used to identify the shape features that best distinguishes the PES from the cervical esophagus. RESULTS The mean age of the cadavers was 77.9 (SD ± 10.6) years, with 67% women. Analysis of the casts confirms that the human PES possesses a kidney-shaped structure at maximal distention, which is discretely different from the adjacent esophagus (P |
| Databáze: | OpenAIRE |
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