Comorbidities in HIV infected patients admitted to County Infectious Diseases Hospital Tg-Mureş in 2013

Autor: Andrea Incze, Nina-Ioana Șincu, Franciska Kristaly, Lucia Carmen Chiriac, Erzsébet Iringó Zaharia-Kézdi
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: BMC Infectious Diseases
ISSN: 1471-2334
Popis: The prevalence and incidence of comorbidities in HIVinfected patients has varied over the past 30 years, depending on the studied population. The purpose of this paper is to review the various conditions registered in HIV-positive patients admitted to the 1st Infectious Diseases Clinic of Tg-Mures. We performed a retrospective cross-sectional study, on 124 HIV infected patients (average age 27 years, 49 female, 85 subjects in AIDS stage), admitted to the HIV Department of the 1st Infectious Diseases Clinic of TgMures during January – December 2013 (253 hospitalizations, overall 2,415 days, median hospital stay 7 days). Co-infections (viral hepatitis, tuberculosis, bacterial, fungal, parasitic and other viral conditions), as well as pluri-organic comorbidities were noted and correlated to gender, level of immune-deficiency, history of HIV infection, adherence to antiretroviral therapy and outcome. Statistical analysis was performed with MannWhitney non parametric test. Patients had an average of 6 comorbidities such as: 98 various bacterial, viral, fungal and parasitic infections, 91 hematologic disorders, 83 metabolic disorders, 77 gastrointestinal conditions, 68 acute respiratory disease cases, 43 neurological issues, 39 mental health problems, 35 hepatitis B infection, 32 chronic respiratory diseases, 25 cases of tuberculosis, 24 bone disorders, 12 cardiovascular diseases, 5 sexually transmitted diseases, and 2 malignancies. We registered statistically significant differences regarding the presence of comorbid conditions and gender (male>female, p=0.003), immune status (more comorbidities in patients with LT CD4
Databáze: OpenAIRE