Symptoms Underlying Unawareness of Memory Impairment in Patients With Mild Alzheimer’s Disease
| Autor: | Yoko Nakano, Masatoshi Takeda, Yohoko Takatsuki, Hiroaki Kazui, Keiji Matsumoto, Etsuro Mori, Mamoru Hashimoto, Yoshitaka Ikejiri, Nobutsugu Hirono |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Statistics as Topic Comorbidity Neuropsychological Tests Delusions 03 medical and health sciences 0302 clinical medicine Delusion Alzheimer Disease medicine Humans Memory impairment Memory disorder Affective Symptoms Psychiatry Aged Geriatrics Memory Disorders Cognitive disorder Age Factors Sick Role Cognition Awareness Middle Aged medicine.disease 030227 psychiatry Psychiatry and Mental health Memory Short-Term Frontal lobe Educational Status Female Neurology (clinical) Geriatrics and Gerontology Alzheimer's disease medicine.symptom Mental Status Schedule Psychology 030217 neurology & neurosurgery |
| Zdroj: | Journal of Geriatric Psychiatry and Neurology. 19:3-12 |
| ISSN: | 1552-5708 0891-9887 |
| Popis: | Patients with Alzheimer’s disease (AD) are often unaware of their cognitive impairment. This unawareness might have a multifactorial etiology, including impairment of cognitive domains and psychiatric symptoms. We conducted this study to determine the factors underlying unawareness of memory impairment (UMI) in patients with AD. In 103 patients with mild AD, the UMI was quantified as the difference between the patient’s self-rating and the rating of the patient’s caregiver on a standardized memory questionnaire system, the Everyday Memory Checklist. We then examined the relationships between UMI and memory, attention, language, visuospatial/constructive perception, frontal lobe function, and psychiatric symptoms. UMI was positively associated with memory impairment and delusions when effects of age, sex, and education were partialled out, suggesting that these symptoms are involved in the formation of UMI in the patients. Thus, existing treatments for memory impairment and delusions may be beneficial for increasing the awareness of mild AD patients of their cognitive impairment. |
| Databáze: | OpenAIRE |
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