Serotonin selectively inhibits growth cone motility and synaptogenesis of specific identified neurons
| Autor: | S. B. Kater, Philip G. Haydon, D. P. McCobb |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
medicine.medical_specialty
Serotonin Snails Synaptogenesis Neurotransmission Biology Animal Population Groups Synaptic Transmission Synapse chemistry.chemical_compound Cellular neuroscience Internal medicine medicine Animals Neurotransmitter Growth cone Cells Cultured Neurons Multidisciplinary food and beverages Cell biology medicine.anatomical_structure Endocrinology nervous system chemistry Synapses Neuron Non-spiking neuron |
| Zdroj: | Science (New York, N.Y.). 226(4674) |
| ISSN: | 0036-8075 |
| Popis: | The motile activity of growth cones of specific identified neurons is inhibited by the neurotransmitter serotonin, although other identified neurons are unaffected. As a consequence, affected neurons are unable to form electrical synapses, whereas other neurons whose growth is unaffected can still interconnect. This result demonstrates that neurotransmitters can play a prominent role in regulating neuronal architecture and connectivity in addition to their classical role in neurotransmission. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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