A micropillar-based microfluidic viscometer for Newtonian and non-Newtonian fluids
| Autor: | Ahmet Erten, Ali Cenk Aksu, Ozlem Yalcin, Aysenur Eser, Melikhan Tanyeri, Alper Kiraz, Adil Mustafa |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Glycerol
Calibration curve Microfluidics 02 engineering and technology 01 natural sciences Biochemistry Viscoelasticity Analytical Chemistry Rheology Deflection (engineering) Newtonian fluid Humans Environmental Chemistry Composite material Spectroscopy Viscosity Chemistry 010401 analytical chemistry Viscometer 021001 nanoscience & nanotechnology Non-Newtonian fluid 0104 chemical sciences Calibration 0210 nano-technology |
| Zdroj: | Analytica Chimica Acta. 1135:107-115 |
| ISSN: | 0003-2670 |
| DOI: | 10.1016/j.aca.2020.07.039 |
| Popis: | In this study, a novel viscosity measurement technique based on measuring the deflection of flexible (poly) dimethylsiloxane (PDMS) micropillars is presented. The experimental results show a nonlinear relationship between fluid viscosity and the deflection of micropillars due to viscoelastic properties of PDMS. A calibration curve, demonstrating this nonlinear relationship, is generated, and used to determine the viscosity of an unknown fluid. Using our method, viscosity measurements for Newtonian fluids (glycerol/water solutions) can be performed within 2-100 cP at shear rates gamma = 60.5-398.4 s(-1). We also measured viscosity of human whole blood samples (non-Newtonian fluid) yielding 2.7-5.1 cP at shear rates gamma = 120-345.1 s(-1), which compares well with measurements using conventional rotational vis-cometers (3.6-5.7 cP). With a sensitivity better than 0.5 cP, this method has the potential to be used as a portable microfluidic viscometer for real-time rheological studies. (C) 2020 Elsevier B.V. All rights reserved. |
| Databáze: | OpenAIRE |
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